Research
Research Field
Proteomics & Biomarker Development: Diagnosing Type-2 Diabetes, Pancreatic Cancer, Hepatocarcinoma and psychiatric diseases, using human blood analyzed by LC-MS. With LC-MS, small amount of proteins can be accurately quantified. Combining multiple protein biomarkers using machine learning techniques, we could have diagnosed patients from healthy individual with better performance than conventional diagnosing tools but less cost.Keyword
Proteomics, Mass Spectrometry,Education
- BE, Biochemistry, SNU (1982)
- MS, Bioengineering, KAIST (1984)
- Ph.D., Chemistry & Biochemistry, University of Texas at Austin (1992)
Career
- Postdoctoral research, Dr. Thomas Steitz (2009 Nobel Laureate) - Yale University (1994)
- Staff Scientist, Washington University (1999 - 2001)
- Visiting PI , Fred Hutchinson Cancer Research Center (2010 - 2011)
- International Journal, Journal of Integrated OMICS, Associated editors-Asia, ISSN 2182-0287 (2012 - present)
- International Journal, Journal of Integrated OMICS, Associated editors-Asia, ISSN 2182-0287 (2012 - present)
- International Journal, Columbia International Publishing, Editorial Board Member, American Journal of Molecular and Cellular Biology (2011 - present)
- International Journal, Scientific Reports, Editorial Board Member, Nature Journal Publishing (2015 - present)
- President of KHUPO (2021-present)
Publication
- Dongyoon Shin Sang Jin Rhee, Jihyeon Lee, Injoon Yeo, Misol Do, Eun-Jeong Joo, Hee Yeon Jung, Sungwon Roh, Sang-Hyuk Lee, Hyeyoung Kim, Minji Bang, Kyu Young Lee, Jun Soo Kwon, Kyooseob Ha, Yong Min Ahn, and Youngsoo Kim (2021) Quantitative proteomic approach for discriminating major depressive disorder and bipolar disorder by multiple reaction monitoring-mass spectrometry, J. Proteome Research, 2021 May 7. doi: 10.1021/acs.jproteome.1c00058.,
- Jihyeon Lee, Young-Suk Lim, Jeong-Hoon Lee, Geum-Youn Gwak, Misol Do, Injoon Yeo, Dongyoon Shin, Dohyun Han, Taesung Park and Youngsoo Kim (2021) Inclusive Quantification Assay of Serum Des-γ-Carboxyprothrombin Proteoforms for HCC Surveillance via Targeted Mass Spectrometry, Hepatology Communications, 12 June 2021, doi.org/10.1002/hep4.1752
- Minsoo Son, Hongbeom Kim, Dohyun Han, Yoseop Kim, Iksoo Huh, Youngmin Han, Seung-Mo Hong, Wooil Kwon, Haeryoung Kim, Jin-Young Jang and Youngsoo Kim (2021) A Clinically Applicable 24-Protein Model for Classifying Risk Subgroups in Pancreatic Ductal Adenocarcinomas using Multiple Reaction Monitoring-Mass Spectrometry, Clinical Cancer Research, 27(12):3370-82, DOI:10.1158/1078-0432.CCR-20-3513
- Yoseop Kim, Injoon Yeo, Iksoo Huh, Jaenyeon Kim, Dohyun Han, Jin-Young Jang and Youngsoo Kim (2021) Development and Multiple Validation of the Protein Multi-marker Panel for Diagnosis of Pancreatic Cancer, Clinical Cancer Research, 27(8): 2236-2245, DOI:10.1158/1078-0432.CCR-20-3929
- Jiyoung Kim, Jengmin Kang, Ye-Lim Kang, Jongmin Woo, Youngsoo Kim, June Huh, Jong-Wan Park (2020) Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer, Nature Communications 11, article number:5436, doi: 10.1038/s41467-020-19263-1