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의과학과 초청세미나 - 이민규 박사(The University of Texas)

조회수 : 4374회

연사 : 이민규 박사(The University of Texas)

연제 : Epigenetic Roles of Histone Methylation Modifiers in Cancer and Differentiation

일시 : 2014년 7월 18일(금) AM 11:00

장소 : 의과학관 115호

문의 : 02-740-8095

대표 발표 논문 :

(2014) UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. Cancer Res. 2014 Mar 15;74(6):1705-17.

(2013) KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling. J Clin Invest. 2013 Dec 2;123(12):5231-46.

(2012) Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4. Genes Dev. 2012 Dec 15;26(24):2749-62.

(2008) Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol. 2008 Feb;28(3):1041-6.

(2007) Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science. 2007 Oct 19;318(5849):447-50.

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