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교수진

김정훈 M.D., Ph.D.

TEL :02-740-8387 FAX : 02-741-3187

email : steph25@snu.ac.kr

전공분야 핵심단어

Retinal & Choroidal Angiogenesis; Blood-retinal Barrier; Retinopathy of Prematurity; Diabetic Retnopathy; Age-related Macular Degeneration; Retinoblastoma

Pure Link

https://snucm.elsevierpure.com/en/persons/jeong-hun-kim

실험실명

망막혈관연구실
Fight against Angiogenesis-Related Blindness (FARB) Laboratory

교수 소개글

망막혈관실험실
망막 및 포도막 혈관신생, 망막혈액장벽, 미숙아망막병증, 선천성 망막병증, 당뇨망막병증, 포도막염, 노인성황반변성, 망막모세포종
교수

교수약력

1992 ～1998 의학사 서울대학교 의과대학(의학)
2001 ～ 2006 의학박사 서울대학교 대학원 의학과(안과학)
2008 ～ 현재 임상교수 서울대학교병원 안과 (소아안과)
2010 ～ 현재 교수 서울대학교 의과대학 의학과 (임상의과학과)
2007 방문연구원 일본심혈관연구센터 (오사카)

연구분야

김정훈 교수는 현재 서울대학교병원 의생명연구원에서 2명의 연구교수를 포함해 7명의 연구원과 4명의 임상 의사를 포함한 12명의 연구진들로 구성된 Fight-against Angiogenesis-Related Blindness (FARB)실험실을 운영하고 있다. 연구 분야는 안과영역에서 실명의 주된 원인인 노인성황반변성, 당뇨망막병증, 미숙아망막병증 및 망막모세포종에 대하여 망막혈액장벽 및 망막혈관신생에 집중하여 분자수준에서의 기전 연구, 동물모델을 통한 전임상 연구 및 환자에서의 임상 연구에 걸친 이행연구(Translational research)에 집중한 연구를 진행하고 있다.

최근연구업적

￭ 최근 3년 대표 업적 5편 (총 업적: SCI논문 172편, 국제 특허 16건, 국내 특허 11건)
[1] An H, Lee S, Lee JM, Jo DH, Kim J, Jeong YS, Heo MJ, Cho CS, Choi H, Seo JH, Hwang S, Lim J, Kim T, Jun HO, Sim J, Lim C, Hur J, Ahn J, Kim HS, Seo SY, Na Y, Kim SH, Lee J, Lee J, Chung SJ, Kim YM, Kim K, Kim SG, Kim JH*, Suh YG*. Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy. J Med Chem. J Med Chem. 2018 Oct 25;61(20):9266-9286. doi: 10.1021/acs.jmedchem.8b00971. Epub 2018 Oct 9. PubMed PMID: 30252468. (*Corresponding author)
[2] Koo T, Park SW, Jo DH, Kim D, Kim JH, Cho HY, Kim J, Kim JH*, Kim JS*. CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration. Nat Commun. 2018 May 10;9(1):1855. doi: 10.1038/s41467-018-04175-y. PubMed PMID: 29748595; PubMed Central PMCID: PMC5945874. (*Corresponding author)
[3] Kim K, Park SW, Kim JH, Lee SH, Kim D, Koo T, Kim KE, Kim JH*, Kim JS*. Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration. Genome Res. 2017 Mar;27(3):419-426. doi: 10.1101/gr.219089.116. Epub 2017 Feb 16. PubMed PMID: 28209587. (*Corresponding author)
[4] Kim E, Koo T, Park SW, Kim D, Kim K, Cho HY, Song DW, Lee KJ, Jung MH, Kim S, Kim JH, Kim JH*, Kim JS*. In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni. Nat Commun. 2017 Feb 21;8:14500. doi: 10.1038/ncomms14500. PubMed PMID: 28220790. (*Corresponding author)
[5] Jo DH, Kim JH, Son JG, Dan KS, Song SH, Lee TG, Kim JH*. Nanoparticle-protein complexes mimicking corona formation in ocular environment. Biomaterials. 2016 Dec;109:23-31. doi: 10.1016/j.biomaterials.2016.09.008 PubMed PMID: 27648757. (*Corresponding author)

교수진

성명	실험실명	전공분야핵심단어	연락처
강건욱	분자영상치료 연구실 Molecular Imaging and Therapy Laboratory http://nm.snu.ac.kr/emain.php	Nuclear Medicine, Molecular Imaging, Nanomedcine	02-2072-2803 kangkw@snu.ac.kr
구자록	암연구소 세포생물학연구실, 한국세포주은행 Lab. of Cell Biology, Cancer Research Institute, Korean Cell Line Bank http://cellbank.snu.ac.kr	Establishment and characterization of human cell lines and organoids, NGS analysis and anticancer drug screening (HTS) in cancer cell lines and organoids, exosomal miRNA profiling in liquid biopsy and cancer cells, biorepositories and living banking of cell lines and organoids	02-3668-7919 kujalok@snu.ac.kr
권오빈	대사-신경정신질환 연구실 BRAIN-MD” (Biochemistry Research Applied In Neuropsychiatric & Metabolic Disorders) https://obinkwonlab.wixsite.com/website	METABOLIC DISORDERS, NEUROPSYCHIATRIC DISORDERS	02-740-8240 obinkwon@snu.ac.kr
권오상	모발생물학모낭재생연구실(의학연구혁신센터 3층) Laboratory of Hair Biology and Hair Follicle Regeneration https://snumrc.snu.ac.kr/iheib	Hair biology, Hair Follicle Stem cell research, Wound healing, Alopecia, Regenerative medicine	02-2072-2417 oskwon@snu.ac.kr
권용태	단백질 대사 실험실 Protein Metabolism Laboratory http://ups.snu.ac.kr 단백질대사의학연구센터(Protein Metabolism Medical Research Center, PMMRC) http://www.pmmrc.snu.ac.kr	Protein degradation, N-end rule, ubiquitin-proteasome system, autophagy, arginylation, N-terminal modifications, protein quality control, cardiovascular signaling, neurodegenerative diseases, stress responses, oxygen sensing, cancer stem cells.	02-740-8547 yok5@snu.ac.kr
김동현	숙주미생물상호작용실험실 Host-Microbe Interaction Lab http://microbiota.snu.ac.kr/	Microbiota, Innate Immunity, Herbal Medicine, 미생물과 숙주의 상호작용	02-740-8304 biologokim@snu.ac.kr
김명환	신경회로 및 행동 연구실 Neural Circuits & Behavior Laboratory	Neuroscience, Synapse, Behavior, Electrophysiology, Neuropsychiatric disease	02-740-8377 kmhwany@snu.ac.kr
김범준	분자만성감염질병 실험실 Laboratory of Molecular Chronic Infectious Disease http://biomed.snu.ac.kr/research/kbumjoon/	Tuberculosis Vaccine, cancer vaccine, Moelcular adjuvant, Hepatitis B virus, hepatocellular carcinoma, Mycobacterium tuberculosis, Human immunodeficiency virus	02-740-8316 kbumjoon@snu.ac.kr
김상정	신경생리학 Laboratory of Neurophysiology World Class University Professor http://brain.snu.ac.kr	neural plasticity learning and memory, mechanism of pain, cerebellum, spinal cord	02-740-8229 sangjkim@snu.ac.kr
김성준	심혈관생리-이온통로 연구실 Cardiovascular Physiology-Ion Channel Laboratory http://cvic.snu.ac.kr	Artery, Heart, Ion Channel, Calcium Signaling, Smooth Muscle, Hypoxia, Hypertension, Exercise Effects, Pulmonary Artery, Pulmonary Hypertension	02-740-8230 sjoonkim@snu.ac.kr
김연수	내과학 신장질환-이식면역 연구실 Laboratory for Kidney Disease and Transplantation	Kidney disease, Allogenic transplantation, Tolerance, Antigen Presenting Cell	02-2072-2264 yonsukim@snu.ac.kr
김영수	단백체학/바이오마커 Proteomics & Biomarker Laboratory http://biolab.snu.ac.kr/	Disease Biomarker for Cancer/Metabolic Disease, Proteomics, Post-Translational Modification Proteome Biology	02-740-8073 biolab@snu.ac.kr
김정훈	망막혈관연구실 Fight against Angiogenesis-Related Blindness (FARB) Laboratory	Retinal & Choroidal Angiogenesis; Blood-retinal Barrier; Retinopathy of Prematurity; Diabetic Retnopathy; Age-related Macular Degeneration; Retinoblastoma	02-740-8387 steph25@snu.ac.kr
김종일	유전체의학실험실 Laboratory of Genomic Medicine (http://www.gmi.ac.kr)	Gene mapping, Human genome variation, Cancer genomics, Next generation sequencing, Bioinformatics	02-740-8251 jongil@snu.ac.kr
김주한	생명정보학 SNU Biomedical Informatics (SNUBI) http://www.snubi.org/	bioinformatics, medical informatics, genomics, systems biology, pharmacogenomics	02-740-8320 juhan@snu.ac.kr
김항래	세포면역학실험실 Laboratory of Immunobiology	CD8 memory differentiation/function, T cell anergy, Immune modulation by metabolites/metabolic reprogramming, Epigenetic changes analysis of immune cells by ATAC-Seq, surface topography (mechanobiology)	02-740-8214 hangrae2@snu.ac.kr
김혜선	분자 신경 약리학 실험실 Laboratory of Molecular Neuropharmacology http://biomed.snu.ac.kr/research/neuropharm619/	Alzheimer’s disease, Autism spectrum disorder, Neurological disease, Brain neural circuit, Non-coding RNA, Neural stem cell	02-740-8298 hyisun@snu.ac.kr
김혜영	점막 면역 실험실 Laboratory of mucosal immunity http://biomed.snu.ac.kr/research/LMI2015	Allergic disease, Mucosal immunology, Innate immunity	02)740-8970 hykim11@snu.ac.kr
묵인희	알츠하이머병 병인기전 연구실 Laboratory of Alzheimer's disease pathogenesis http://www.alzlab.co.kr	Neurodegenerative diseases, Alzheimer’s disease, proteomics, proteases, brain aging	02-740-8245 inhee@snu.ac.kr
박상민	헬스 시스템 데이터 사이언스 연구실 Health System Data Science Laboratory	Data science, simulation epidemiology, pharmacoepidemiology, medical big data analysis, cost-effectiveness, quality cancer care, health promotion (cancer survivors, migrants, young adults), deep learning	02-2072-3331 smpark.snuh@gmail.com
박정규	세포분자면역학 실험실 Laboratory of Cellular and Molecular Immunology Laboratory of Immune tolerance and Transplantation immunology (ITTI) http://biomed.snu.ac.kr/research/ITTI	Immunological tolerance, Transplantation immunology, Autoimmune disease, Regulatory T cell, Th17 cell, Islet transplantation, xenotransplantation, exosomes	02-740-8308 chgpark@snu.ac.kr
박종완	미세환경 재구성 연구실 Laboratory of Hypoxia Research http://microenvironment.snu.ac.kr/	hypoxia, hypoxia-inducible factors, gene expression, cancer, angiogenesis	02-740-8289 parkjw@snu.ac.kr
서영호	분자신경기능 연구실 Laboratory of molecular synaptic function http://biomed.snu.ac.kr/research/Molneuro7 https://snucm.elsevierpure.com/en/persons/young-ho-suh	Glutamate receptors, Trafficking, Synaptopathy, Synaptic plasticity	02-3668-7611 suhyho@snu.ac.kr
서인석	TRP칼슘채널실험실 TRP channel research Laboratory http://sites.google.com/site/ smoothmusclesnu/members	transient receptor potential channels, protein-protein interaction, smooth muscle research, calcium homeostasis, GI motility	02-740-8228 insuk@snu.ac.kr
석승혁	마크로파지 실험실 The Laboratory of Macrophages http://macrophage.snu.ac.kr	Discovery of the molecular mechanisms of homeostatic function of macrophages during development, Immune modulating for rewiring macrophage differentiation for macrophage related diseases, Pre-metastatic niche and macrophage exosomes	02-740-8302 lamseok@snu.ac.kr
성승용	시스템면역의학연구소 Wide River Institute of Immunology Seoul National University College of Medicine https://youtu.be/BqWlbbNAXo8	cancer immunotherapy, dendritic cell, hyppo model, regulatory cell, single domain antibody therapeutics	02-740-8301 seongsy@snu.ac.kr
송현범	기생충 숙주 환경 상호작용 연구실 IHoPE(Interaction among Host-Parasite-Environment) Lab 실험실 주소 url: http://ihope.snu.ac.kr/	Parasite, Protozoa, Ocular infection	02-740-8342 hbsong@snu.ac.kr
신현무	면역학/시스템면역학실험실 Systems Immunology Lab at Wide River Institute of Immunology Seoul National University College of Medicine	Systems Immunology, Infectious diseases, Cancer Immunotherapy, Genomics	033-439-8046 hyunmu.shin@snu.ac.kr
신현우	상기도 폐쇄질환 연구실 Obstructive Upper airway Research (OUaR) Laboratory http://sites.google.com/view/ouarlab	Airway Epithelial Remodeling, Intermittent Hypoxia, Obstructive Sleep Apnea, Nasal polyp, Upper Airway Obstruction, Biomarker and Metabolomics	02-740-8285 charlie@snu.ac.kr
염진기	세균 생리학 실험실(Laboratory of Bacterial Physiology, 연구관 320호) https://www.yeomlab.com/	Infectious disease, Bacterial pathogen, Bacteria stress response, Pathogenesis, Antibiotic persistance, Proteolysis, Protein homeostasis	02-740-8305 jinki.yeom@snu.ac.kr
예상규	암줄기세포 & 종양미세환경 연구실 Laboratory of Cancer Stem Cells & Tumor Microenvironment www.stat3.org	STAT3, angiogenesis, cancer stem cells, Inflammatory diseases, T cell development	02-740-8241 sangkyu@snu.ac.kr
유경상	임상약리학 연구실 Clinical Pharmacology and Therapeutics Lab http://cpt.snu.ac.kr	Personalized drug therapy, Clinical Pharmacokinetics and Pharmacodynamics, PK-PD modeling	02-2072-1920 ksyu@snu.ac.kr
윤홍덕	분자생물학/에피제네틱스 에피지놈 리프로그래밍 창의연구단 National Creative Research Center for Epigenome Reprogramming Network http://cern.snu.ac.kr	chromatin dynamics, metabolic checkpoint, transcriptional regulation, histone modification, epigenetics	02-740-8250 hdyoun@snu.ac.kr
이동섭	Laboratory of Immune Systemic Interactome in Cancer & Kidney (ISICK) http://Biomed.snu.ac.kr/research/snuisick	Cancer metastasis, Cancer stem cells, Immune-Cancer cross-talk, Immune regulation, Tissue-resident immune cells, Tissue-Immune cross-talk, Kidney inflammation & homeostasis	02-740-8202 dlee5522@snu.ac.kr
이민재	단백질 다이나믹스 연구실 Protein Dynamics Laboratory https://sites.google.com/site/upsbiochem/	ubiquitin, proteasome, autophagy, protein degradation, protein homeostasis, proteostasis, Alzheimer's disease, Parkinson's disease, neurodegenerative disease	02-740-8254 minjlee@snu.ac.kr
이승재	신경질환실험실 Laboratory of Neurological Disease http://biomed.snu.ac.kr/research/LND/	Neurodegenerative diseases, Parkinson’s disease, dementia, protein aggregation, neuroinflammation	02-3668-7037 sjlee66@snu.ac.kr
이용석	신경생리학 실험실 Laboratory of Neurophysiology (http://brain.snu.ac.kr)	learning and memory, neurodevelopmental disorders, memory enhancement, hippocampus, molecular neurobiology	02-740-8225 yongseok7@snu.ac.kr
이원우	자가면역 & 염증 연구실 Laboratory of Autoimmunity and Inflammation http://biomed.snu.ac.kr/research/LAI/	autoimmunity, immunosenescence, inflammatory monocytes/macrophage, cell-signaling network, zinc homeostasis, human immunology	02-740-8303 wonwoolee@snu.ac.kr
이진구	세포 중개의학 실험실 (Lab of Cellular and Translational Medicine, 연구관 230호)	Cancer Organoid, 3D drug screening, Precision Oncologuy, Translational Medicine	02-740-8201 jinkulee@snu.ac.kr
이창한	항체/면역학 실험실(연구관 423호 실험실) Antibody Therapeutics and Cancer Immunology https://www.theleelab-antibody.com/	Antibody discovery and engineering, Fc receptors, Complement, Effector cells, Onco-immunology	02-740-8289 chlee-antibody@snu.ac.kr
이철환	후성유전학/분자약리학 실험실(연구관 619-2호 실험실) http://chulhwanlab.com/	발생 및 암에서의 유전자 발현 조절 메커니즘 연구, 히스톤 변형/돌연변이 연구	02-740-8133 chulhwan@snu.ac.kr
장성호	신경기능 및 바이오이미징 연구실 Laboratory of Neural Functions and Bioimaging http://biomed.snu.ac.kr/research/nfi/	Synaptic physiology, neurotransmission, exo-endocytosis, short-term synaptic plasticity, pre-and post-synaptic morphogenesis, neurodegenerative diseases, Live cell imaging/super-resolution imaging	02-740-8918 sunghoe@snu.ac.kr
장은화	심혈관 생리학, 고혈압, 대사질환, 심장 허혈-재관류, 심혈관보호 연구실 Cardiovascular Physiology, Hypertension, Metabolic disorder, Cardiac ischemic-reperfusion, cardiovascular protection http://cvic.snu.ac.kr	Cardiovascular myocyte electrophysiology & physiology, excitation-contraction coupling, fat metabolism & mitochondria, hypertension, ischemia-reperfusion of the heart, nitric oxide, reactive oxygen species, exercise	02-740-8223 yinzhang@snu.ac.kr
전양숙	분자생리학/에피제네틱스 Molecular Physiology and Chromatin dynamics http://microenvironment.snu.ac.kr	Signal transduction, posttranslational regulation, Chromatin dynamics	02-740-8909 chunys@snu.ac.kr
전주홍	분자생리학 실험실 Molecular Physiology Laboratory http://jeonslab.snu.ac.kr/	Cell signaling and molecular physiology, Signaling homeostasis and epistasis, Drug resistance and cell resilience.	02-740-8399 jhjeon2@snu.ac.kr
정기훈	Lab of Cancer Immunology and In Vivo Imaging http://www.junglab.snu.ac.kr/	cancer immunology, in vivo imaging, vascular biology, tumor microenvironment, intravital multi-photon microscopy, drug development	02-740-8207 keehoon.jung@snu.ac.kr
정두현	면역조절실험실(Laboratory of Immune Regulation) http://lir.snu.ac.kr	Immune regulation, NKT cells, Immunometabolism, Autoimmunity, Tumor immunity	02-740-8915 doohyun@snu.ac.kr
정재민	방사성의약품개발 연구실 Laboratory of Radiopharmaceutical Development http://radiopharmaceutical.snu.ac.kr	Radiopharmaceutical, Molecular Imaging, Radionuclide Therapy, Neural Network Plasticity Imaging	02-2072-3805 jmjng@snu.ac.kr
정준호	항체 공학 실험실 Laboratory of Antibody Engineering http://www.junholab.com	Therapeutic antibody, Protein Engineering, Immune profiling with machine learning algorithm	02-740-8242 jjhchung@snu.ac.kr, junhochungmd@gmail.com
정진호	피부과학교실 Laboratory of Cutaneous Aging Research & Hair Biology http://iheib.snu.ac.kr/main/tmpl/sub_main.php?m_cd=5&m_id=0101	Skin aging, Photobiology, Geriatric dermatology, Anti-skin aging, Cosmetology	02-2072-2414 jhchung@snu.ac.kr
조남혁	백신면역학실험실 Laboratory of Immunoarchitectonics for Vaccines (http://biomed.snu.ac.kr/research/immunoarch/)	Rickettsia, gamma-herpesvirus, host-pathogen interactions, viral oncogenesis, cancer immunotherapy	02-740-8392 chonh@snu.ac.kr
조성엽	생화학/정밀분자종양학 연구실 Laboratory of Precision and Molecular Oncology http://biomed.snu.ac.kr/research/LPMO227/	Cancer genomics, Targeted therapeutics, Drug resistance, Cancer immunotherapy, Patient-derived xenograft model	02-740-8241 csybio@snu.ac.kr
조정현	혈관미세환경연구실 Vascular Microenvironment Laboratory http://microenvironment.snu.ac.kr/	Angiogenesis, Endothelial cell, Angiopoietin, Tumor angiogenesis	02-740-8283 iamhyun@snu.ac.kr
조주연	약리대사체학 연구실 Pharmaco-metabolomics Laboratory http://cpt.snu.ac.kr/	Personalized drug therapy, Metabolomics, Pharmacometabolomics, Pharmacogenomics	02-740-8286 joocho@snu.ac.kr
최경호	분자면역학, Laboratory of Molecular Immunology http://tcell.snu.ac.kr/	T cell tolerance, T cell anergy, regulatory T cell, anti-tumor T cell therapy, autoimmune diseases	02-740-8244 khchoi@snu.ac.kr
최무림	기능유전체학 Functional Genomics lab (https://www.snugenomics.com/)	Functional genomics, translational genomics, human genetics, developmental biology	02-740-8912 murimchoi@snu.ac.kr
최윤수	면역·병리 항체조절 실험실 Regulation of Immunological·Pathological Ab Laboratory	follicular helper T cell differentiation, high affinity antibodies, vaccination, autoantibodies	02-3668-7377 younsoo94@snu.ac.kr
최은영	면역유전학 Immunogentic Laboratory http://immunogenetics.snu.ac.kr/	T cell development, Transplantation Immunology, Cancer Immune therapy, Autoimmune disease.	02-740-8919 eycii@snu.ac.kr
최지엽	행동 역학 연구실 Behavioral Systems Epidemiology Lab https://sites.google.com/view/behavepi	Epidemiology, Behavior, Medication, Susceptibility, Prevention	02-740-8922 miso77@snu.ac.kr
최형진	대사조절 기능신경해부학 연구실 Functional Neuroanatomy of Metabolism Regulation http://fnmr.snu.ac.kr/	Functional Neuroanatomy, Metabolism Regulation	02-740-8204 hjchoi@snu.ac.kr
한범	유전체 생물정보학 연구실 Genomics & Bioinformatics Laboratory http://hanlab.snu.ac.kr	Bioinformatics, Genomics, Statistical Genetics, Computational Biology, Human Leukocyte Antigen	02-3668-7618 buhm.han@snu.ac.kr
Aaron Ciechanover	Joint laboratory with Yong Tae Kwon Protein turnover, N-end rule pathway Website (SNU): http://ups.snu.ac.kr Protein Metabolism Medical Research Center: Coming soon	The Ubiquitin-Proteasome System (UPS), Protein Turnover, Apoptosis, Cancer, Personalized Medicine	02-740-8547 yok5@snu.ac.kr