Department of Biomedical Sciences, SNU

2012년 2학기 우수의과학자 초청 세미나 10주차

  • 연사 : 강수민 교수(Emory U.)
  • 연제 : Signaling and targeting of RSK2 in human malignancies
  • 일시 : 2012년 11월 21일(수) PM 2:00
  • 장소 : 함춘강의실
  • 문의 : 02-740-8095
대표 발표 논문 : (2012) Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis by controlling intracellular levels of 3-phosphoglycerate and 2-phosphoglycerate. Cancer Cell (2011) Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Mol Cell (2011) p90RSK2 is essential for FLT3-ITD-, but dispensable for BCR-ABL-induced myeloid leukemia. Blood (2007) FGFR3 activates RSK2 to mediate hematopoietic transformation through both tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell (2007) 14-3-3 integrates pro-survival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1 transformed hematopoietic cells. Blood