Department of Biomedical Sciences, SNU

2013년 2학기 우수의과학자 초청 세미나 2주차

  • 연사 : 이서구 교수(연세대학교)
  • 연제 : The Peroxiredoxin Story: From the Incidentals to the Fundamentals
  • 일시 : 2013년 9월 11일(수) PM 2:00
  • 장소 : 함춘강의실
  • 문의 : 02-740-8095
대표발표논문 : Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage. Cell Metab. 2013 Jan 8;17(1):73-84. Feedback control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation of peroxiredoxin III in mitochondria. Mol Cell. 2012 Jun 8;46(5):584-94. Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver. Hepatology. 2011 Mar;53(3):945-53. Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell. 2010 Feb 19;140(4):517-28. Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors. Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16419-24.