Department of Biomedical Sciences, SNU

2013년 2학기 우수의과학자 초청 세미나 4주차

  • 연사 : 이진환 박사(한국표준과학연구원)
  • 연제 : Probing Protein Complex Dynamics with Mass Spectrometry
  • 일시 : 2013년 10월 2일(수) PM 2:00
  • 장소 : 함춘강의실
  • 문의 : 02-740-8095
대표발표논문: Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell. 2013 Mar 28;153(1):206-15. Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking. Mol Cell Proteomics. 2012 Jun;11(6):M111.016444. Designer reagents for mass spectrometry-based proteomics: clickable cross-linkers for elucidation of protein structures and interactions. Anal Chem. 2012 Mar 20;84(6):2662-9. Click chemistry facilitates formation of reporter ions and simplified synthesis of amine-reactive multiplexed isobaric tags for protein quantification. J Am Chem Soc. 2012 Feb 8;134(5):2672-80. The steady-state repertoire of human SCF ubiquitin ligase complexes does not require ongoing Nedd8 conjugation. Mol Cell Proteomics. 2011 May;10(5):M110.006460.