Department of Biomedical Sciences, SNU

2010년 2학기 우수의과학자 초청 세미나 6주차

  • 연사 : 임대식 교수(KAIST)
  • 연제 : Mammalian Hippo signaling pathway and Tumorigenesis
  • 일시 : 2010년 10월 21일(목) AM 10:00
  • 장소 : 함춘강의실
  • 문의 : 740-8095
대표 발표 논문: The Hippo–Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis, Proc Natl Acad Sci USA. 2010. SKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma Prognosis, GASTROENTEROLOGY. 2009. Aurora B-mediated phosphorylation of RASSF1A maintains proper cytokinesis by recruiting Syntaxin16 to the midzone and midbody, Cancer Res. 2009. The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex. EMBO J. 2008.   ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell. 2008. A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J. 2008.