2010년 2학기 우수의과학자 초청 세미나 8주차
- 연사 : 김자은 교수 (경희대학교)
- 연제 : DOT1L histone methyltransferase regulates proliferation of cancer cells
- 일시 : 2010년 11월 11일(목) AM 10:00
- 장소 : 함춘강의실
- 문의 : 740-8095
대표발표논문:
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. Mol Cell. 2010.
BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Mol Cell. 2010.
Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage. J Biol Chem. 2009.
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol. 2008.
DBC1 is a negative regulator of SIRT1. Nature. 2008
