2008년도 1학기 우수의과학자 특강 12주차
- Speaker : 권용태 박사 (U.Pittsburgh)
- Topic : N-end Rule Ubiquitin-Proteasome System: Its Role in Cardiovascular Signaling, Meiosis, and Other Processes
- Date : 2008년 6월 5일(목) 오후 1시30분
- Location : 함춘강의실
- Inquiry : 의과학과 사무실 02-740-8095
주요 발표 논문:
Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway. Proc. Natl. Acad. Sci. USA. 2008
Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proc. Natl. Acad. Sci. USA. 2006
Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nat. Genet. 2005
RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proc. Natl. Acad. Sci. USA. 2005
Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Mol. Cell. Biol. 2003
