2013년 2학기 우수의과학자 초청 세미나 5주차
- Speaker : 오성환 박사(Harvard Medical School)
한재석 박사(Sanford Burnham Medical Institute) - Topic : 2pm : Regulation of Host Immunity by Endogenous and Symbiotic Lipid Mediators,
3pm : Endoplasmic Reticulum (ER) stress and its pathophysiological implications - Date : 2013년 10월 16일(수) PM 2:00
- Location : 함춘강의실
- Inquiry : 02-740-8095
<오성환 박사 대표발표논문>
(2012)Antiinflammatory and pro-resolving actions of Resolvin D1 and 17R-Resolvin D1 in allergic airways responses. J. immunol. 189: 1983-91.
(2012)Infection regulates proresolving mediators that lower antibiotic requirements. Nature. 484: 524-528.
(2012)Resolvin E2 formation and impact in inflammation-resolution. J Immunol. 188:4527-4534.
(2012)Genotype-Directed Therapies Optimize Tuberculosis Outcome By Tuning Host Inflammation. Cell. 148:434-446.
(2011) Novel 18S-E-series Resolvins, Stereoselective Biosynthesis and Pro-resolving Actions. J. Clin. Invest. 121:569-81.
<한재석 박사 대표발표논문>
(2013). ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nature cell biology 15(5):481-90.
(2013) Phosphorylation of eukaryotic translation initiation factor 2 alpha induces CHOP to suppress adipocyte differentiation. Diabetologia 56(4): 911-924
(2012) IRE1 alpha-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis. Cell Metab 16(4): 473-486
(2012) RNA surveillance is required for endoplasmic reticulum homeostasis. Proc Natl Acad Sci U S A 109(21): 8079-8084.
(2011) Remission of Diabetes by Insulin Gene Therapy Using a Hepatocyte-Specific and Glucose-Responsive Synthetic Promoter. Mol Therapy 19(3):470-8