2014년 1학기 우수의과학자 초청 세미나 11주차
- Speaker : 정용근 교수(서울대학교)
- Topic : Critical factor of amyloid toxicity and tau phosphorylation in Alzheimer’s disease
- Date : 2014년 5월 20일(화) PM 2:00
- Location : 함춘강의실
- Inquiry : 02-740-8095
대표 발표 논문:
The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Nat Commun. 2014;5:3351.
OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin. Cell Mol Life Sci. 2013 Nov 24.
Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E54-61.
Overexpression of Atg5 in mice activates autophagy and extends lifespan. Nat Commun. 2013;4:2300.
BECN1/Beclin 1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid β 42. Autophagy. 2013 Dec;9(12):2009-21.