Department of Biomedical Sciences, SNU

2009년도 1학기 우수의과학자 초청 세미나 5주차

  • Speaker : David Kang 박사 (UC San Diego)
  • Topic : Role of the LRP-RanBP9 pathway in Alzheimer
  • Date : 2009년 4월 8일(수) 오전 9:30
  • Location : 함춘강의실
  • Inquiry : 740-8095
주요 발표논문 Presenilin couples the paired phosphorylation of β-catenin independent of Axin: Implications for β-catenin activation in tumorigenesis. Cell. 2002 Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors: Selectivity of PS2 in platelet-derived growth factor signaling. J. Biol. Chem. 2005 Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway. FASEB J. 2007 C-terminal 37 residues of LRP promote amyloidogenic processing of APP independent of FE65. J. Cell. Mol. Med. 2008 Novel role of RanBP9 in BACE1 processing of APP and amyloid beta peptide generation. J. Neurosci. 2008