의과학과 초청세미나 - 서재홍 박사(Harvard Medical School)
- Speaker : 서재홍 박사(Harvard Medical School)
- Topic : ADAM10, The Major α-Secretase for Amyloid Precursor Protein, Is A Potential Alpha SECRETase for Alzheimer’s Disease
- Date : 2013년 10월 28일(월) PM 2:00
- Location : 의과학관 115호
- Inquiry : 02-740-8095
대표발표논문 :
Tanzi RE. ADAM10 Missense Mutations Potentiate -Amyloid Accumulation by Impairing Prodomain Chaperone Function. Neuron 2013; 80:385-401.
FE65 proteins Regulate NMDA Receptor Activation-induced Amyloid Precursor Protein Processing. J Neurochem 2011; 119:377-388.
Hypoxic Ischemia and Proteasome Dysfunction Alter Tau Isoform Ratio by Inhibiting Exon 10 Splicing. J Neurochem 2010; 114:160-170.
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate alpha-secretase activity. Hum Mol Genet 2009; 18:3987-3996.
