Department of Biomedical Sciences, SNU
KOR

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Faculty

Seok, seung-hyeok

DVM, PhD, DKCLAM / Professor
The Laboratory of Macrophages
TEL +82-2-740-8302, 8077
FAX 02-740-0881
E-MAIL lamseok@snu.ac.kr
WEBSITE http://macrophage.snu.ac.kr

Research

Research Field
Pure Link
https://snucm.elsevierpure.com/en/persons/seung-hyeok-seok
Keyword
Discovery of the molecular mechanisms of homeostatic function of macrophages during development, Immune modulating for rewiring macrophage differentiation for macrophage related diseases, Pre-metastat
Intensive Major
# Immune
# Infectious disease

Career

  • 2007 PostDoc, Seoul National Universtiy, College of Pharmacy
  • 2008 Lecturer, Clinical professor of Seoul National University Hospital
  • 2010 Assistant, Associate, Full Professor of Seoul National University, College of Medicine, Dept. Microbiology and Immunology/Biomedical Sciences

Publication

  1. Na YR, Jung D, Stakenborg M, Jang H, Gu GJ, Jeong MR, Suh SY, Kim HJ, Kwon YH, Sung TS, Ryoo SB, Park KJ, Im JP, Lee YS, Han H, Park B, Lee S, Kim D, Lee HS, Cleynen I, Matteoli G*, Seok SH *. Prostaglandin E2 Receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation. Gut. 2021 Feb 8. (IF 23.059)
  2. Na YR, Stakenborg M, Seok SH*, Matteoli G*. Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD. Nature Reviews Gastroenterology & Hepatology. 2019 Jul 16. Doi: 10.1038/s41575-019-0172-4. (IF 46.802)
  3. Na YR, Kwon JW, Kim DY, Chung H, Song J, Jung D, Quan H, Kim D, Kim JS, Ju YW, Han W, Ryu HS, Lee YS, Hong JJ, Seok SH *. Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages. Cell Rep. 2020 May 12;31(6) (IF 9.432)
  4. Kim H, Chung H, Kim J, Choi DH, Shin Y, Kang YG, Kim BM, Seo SU, Chung S *, Seok SH *. Macrophages-triggered sequential remodeling of endothelium-interstitial matrix to form pre-metastatic niche in microfluidic tumor microenvironment. Advanced Science. Apr 10; 6(11), 2019 (IF 16.806)
  5. Na YR, Je S, Seok SH. Metabolic features of macrophages in inflammatory diseases and cancer. Cancer Lett. 2018 Jan 28;413:46-58. doi: 10.1016/j.canlet.2017.10.044. (IF 8.679)
List
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