Department of Biomedical Sciences, SNU

Faculty

Faculty

Research

Research Field
There are three main areas of research that we are doing in our 'Institute of Human-Environment Interface Biology (IHEIB)'. First, we are investigating how various environmental stimuli from external environment cause skin aging, and we are studying prevention and treatment of skin aging. Second, we are identifying the various components of the skin such as collagen fibers, elastic fibers, proteoglycans, and glycosaminglycans in aging skin, to clarify what causes them, and to identify underlying molecular mechanisms. Based on the results, we are developing methods to prevent and treat skin aging process. Third, recent studies have revealed that the effects of skin aging on the function of other organs in the human body.
Keyword
Skin aging, Photobiology, Geriatric dermatology, Anti-skin aging, Cosmetology

Publication

  1. Skullcapflavone II Suppresses TNF-α/IFN-γ-Induced TARC, MDC, and CTSS Production in HaCaT Cells. Int J Mol Sci. 2021, 22, 12, 6428
  2. A natural compound harmine decreases melanin synthesis through regulation of the DYRK1A/NFATC3 pathway. J Dermatol Sci. 2021,103,1,16-24.
  3. Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95. Int J Mol Sci. 2021, 22, 9, 4477
  4. Palmitoyl-KVK-L-ascorbic acid conjugate improves matrix abnormality associated with skin aging via epigenetic regulation. J Dermatol Sci. 2021, 101, 3, 214-217
  5. Increased Histone Acetylation and Decreased Expression of Specific Histone Deacetylases in Ultraviolet-Irradiated and Intrinsically Aged Human Skin In Vivo. Int J Mol Sci. 2021, 22, 4, 2032