Park, jong-wan

M.D., Ph.D. / Professor

Laboratory of Hypoxia Research

TEL +82-2-740-8289

FAX 02-745-7996

E-MAIL parkjw@snu.ac.kr

WEBSITE http://microenvironment.snu.ac.kr/

hypoxia, hypoxia-inducible factors, gene expression, cancer, angiogenesis

# Molecular cell

# Metabolic convergence

Hypoxia-inducible Factor 1 Mediates Nasal Polypogenesis by Inducing Epithelial-to-Mesenchymal Transition. Am J Respir Crit Care Med. 2012 May 1, 185(9): 944-54.
Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro. Hepatology. 2011 Jan;53(1):171-180.
HIF-2alpha Enhances beta-Catenin/TCF-Driven Transcription by Interacting with beta-Catenin. Cancer Res. 2010 Dec 15;70(24):10101-11.
Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-inducible Factor 1. Molecular Cell 2010 June 25; 38: 864-878.
HIF-1a obstructs a Wnt-signaling pathway by inhibiting the hARD1-mediated activation of b-catenin. Cancer Res. 2008 Jul 1;68(13):5177-84.

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