Kim, myoung-hwan
Ph.D. / Associate professor
Research
Research Field
Neurons are interconnected with one another to form neural circuits, functional entities of neuronal population, in the brain. Neural circuits respond to environmental stimuli and guide appropriate behaviors in animals. However, permanent alterations in neural circuit by biological or environmental factors produce abnormal behaviors and lead to psychiatric diseases. Dr. Myoung-Hwan Kim is currently investigating the interplay between gene, environment, and neural circuit using gene knockout mice to better understand the mechanism between permanent modification of neural circuits and psychiatric disease. Combining electrophysiology, cellular & molecular biology, and behavioral neurogenetics, Dr. Myoung-Hwan Kim’s group investigates gene-to-behavior pathways in psychiatric disease.Main topics of research:
1) Neural mechanisms underlying stress susceptibility and behavioral despair
2) Intellectual disability in inheritable metabolic disease.
Keyword
Neuroscience, Synapse, Behavior, Electrophysiology, Neuropsychiatric diseaseEducation
- 2001 B.A., Kyungpook National University, Genetic Engineering
- 2005 Ph.D., Seoul National University College of Medicine, Physiology
Career
- 2005-2006 PostDoc, Seoul National University College of Medicine, Physiology
- 2006-2009 PostDoc, KAIST, Biological sciences
- 2010 Assistant research professor, KAIST, Biological Sciences
- 2018~2019 Visiting Assistant Professor, Yale University, School of Medicine
- 2010~present Assistant professor, Associate professor, Seoul National University College of Medicine
Publication
- Kang M, Yoon SH, Kang M, Park SP, Song SW, Kim J, Lee S, Park DH, Song JM, Kim B, Park KH, Joe EH, Woo HG, Park SH, Kaang BK, Han D*, Lee YS*, Kim MH*, Suh YH*. Cell Rep. 44(1):115155 (2025). (*co-corresponding author)
- Yoon SH, Song WS, Chung G, Kim SJ, Kim MH. Activity in the dorsal hippocampus-mPFC circuit modulates stress-coping strategies during inescapable stress. Exp Mol Med. 56(9):1921-1935 (2024).
- Song WS, Cho YS, Oh SP, Yoon SH, Kim YS, Kim MH. Cognitive and behavioral effects of the anti-epileptic drug cenobamate (YKP3089) and underlying synaptic and cellular mechanisms. Neuropharmacology. 221:109292 (2022).
- Bae YS, Yoon SH, Kim YS, Oh SP, Song WS, Cha JH, Kim MH. Suppression of exaggerated NMDAR activity by memantine treatment ameliorates neurological and behavioral deficits in aminopeptidase P1-deficient mice. Exp Mol Med. 54 (8):1109-1124 (2022).
- Yoon SH, Song WS, Oh SP, Kim YS, Kim MH. The phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain. Mol Brain. 14(1):142 (2021).
- Yoon SH, Bae YS, Oh SP, Song WS, Chang H, Kim MH. Altered hippocampal gene expression, glial cell population, and neuronal excitability in aminopeptidase P1 deficiency. Sci Rep. 11(1):932 (2021).
